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Urokinase 50000iu Inj
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Urokinase (50000IU)
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About Urokinase 50000iu Inj
Urokinase 50000iu Inj (Urokinase) is a powerful clot-busting medication used only under strict medical supervision to treat life-threatening blood clots like PE and DVT. It's administered intravenously in a hospital setting with continuous monitoring. Serious side effects like bleeding are possible. Always follow your doctor's instructions precisely and immediately report any unusual symptoms.
Ingredients of Urokinase 50000iu Inj

    Urokinase

    Is the primary active ingredient. specific formulations may contain inactive ingredients like sodium chloride or mannitol; always check the product label for a complete list.

Direction for Use of Urokinase 50000iu Inj

    Treatment of acute massive pulmonary embolism (PE)

    Treatment of deep vein thrombosis (DVT) when thrombolysis is indicated

    Dissolution of clots in various other conditions (as determined by a physician)

    Urokinase may also be used offlabel for certain other conditions, however, this should be done only under strict medical supervision.

How Urokinase 50000iu Inj Works

Urokinase 50000iu Inj (Urokinase) is a thrombolytic agent (clot-buster). It activates plasminogen, converting it to plasmin, an enzyme that breaks down fibrin, the protein that forms blood clots. This action leads to clot lysis (dissolution).

Storage and Handling of Urokinase 50000iu Inj

Store at the temperature specified on the product label. Usually this is refrigeration. Protect from light and moisture. Dispose of unused medication properly according to your local regulations.

Dosage of Urokinase 50000iu Inj

    Dosage is highly individualized and depends on the specific condition, severity, and patient factors. It's administered intravenously (IV) by healthcare professionals only. Never self-administer urokinase.

    The dosage regimen should be strictly followed as directed by your physician. Do not alter the dosage or frequency without consulting your physician.

    Continuous monitoring by healthcare providers is essential during treatment with urokinase.

Side effects of Urokinase 50000iu Inj

    Hypotension (low blood pressure)

    Nausea

    Vomiting

    Fever

    Allergic reactions (rash, itching, swelling)

    Anaphylaxis (severe, lifethreatening allergic reaction)

Safety Consideration or Warnings
    Alcohol Consumption

    Alcohol consumption should be avoided or limited significantly during treatment with urokinase due to increased risk of bleeding.

    While Driving or Operating Machinery

    Driving or operating machinery may be impaired due to potential side effects like hypotension or allergic reactions. Patients should follow their physician's advice.

    Pregnant & Breastfeeding Women

    Use during pregnancy and breastfeeding is generally avoided unless the potential benefits outweigh the risks. Consult your physician for guidance.

    Children

    Urokinase's use in children is usually determined based on the specific needs and risks assessed by a pediatric specialist.

    Kidney

    Caution is necessary in patients with kidney impairment as the drug's excretion may be affected.

    Liver

    Urokinase use needs to be carefully managed in patients with liver disease. Physician evaluation is crucial.

References

    Refer to the specific product monograph provided by your healthcare professional.

    Consult reputable medical databases like PubMed for scientific information on urokinase.

Last Updated On 16 Aug. 2025 | 12:17 AM (IST)
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