Gentamicin sulfate (the active ingredient)Inactive ingredients (vary depending on the specific formulation – check your medication's label)
Treatment of serious bacterial infections caused by susceptible gramnegative bacteria (e.g., E. coli, Pseudomonas aeruginosa, Klebsiella pneumoniae)
Treatment of certain grampositive bacterial infections (in combination with other antibiotics)
Treatment of infections in patients with compromised immune systems
Treatment of bacterial endocarditis (infection of the heart valves)
Zentivin 80mg Inj (Gentamicin) is an aminoglycoside antibiotic that works by binding to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis and leading to bacterial cell death. This is bactericidal, meaning it kills the bacteria directly.
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Do not use if the solution is cloudy or contains particulate matter. Discard any unused portion after the expiration date.
Dosage is determined by the physician based on the patient's weight, kidney function, and the severity of infection.
Gentamicin is usually administered intravenously (IV) or intramuscularly (IM).
Oral administration is generally not recommended due to poor absorption.
Treatment duration varies depending on the infection and response to therapy; it's typically short-term to minimize toxicity.
Kidney damage (nephrotoxicity)
Hearing loss (ototoxicity)
Nausea
Vomiting
Diarrhea
Rash
Headache
Dizziness
Muscle weakness
Numbness or tingling
Alcohol may exacerbate some side effects; consult your doctor.
Gentamicin can cause dizziness. Avoid driving or operating machinery if affected.
Use only if clearly needed and under strict medical supervision. Risk to fetus and infant should be weighed against benefits.
Dosage adjustment is necessary based on weight and kidney function.
Gentamicin is nephrotoxic (damaging to kidneys); kidney function should be monitored closely.
Gentamicin is primarily eliminated via the kidneys; liver function monitoring is generally not required.
Your doctor or pharmacist
The prescribing information (package insert) for your specific gentamicin product
Reputable medical websites and databases (e.g., MedlinePlus, Drugs.com)
