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Bosentan 62.5mg Tablets
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Pharma & Medical Bureau Of India (Pmbi)
Composition
Bosentan (62.5mg)
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About Bosentan 62.5mg Tablets
Bosentan 62.5mg Tablets (Bosentan) is a medication used to treat pulmonary arterial hypertension (PAH). It works by relaxing blood vessels in the lungs. Common side effects include headache, flushing, and swelling. It's crucial to inform your doctor about your medical history, especially if you have liver or kidney problems. Bosentan is contraindicated during pregnancy and breastfeeding. Regular monitoring of liver and kidney function is essential while taking this medication. Always adhere to your doctor's prescribed dosage and seek immediate medical attention if you experience any severe side effects.
Ingredients of Bosentan 62.5mg Tablets

    Bosentan

    Is the active ingredient.

Direction for Use of Bosentan 62.5mg Tablets

    Pulmonary arterial hypertension (PAH)

    Treatment of PAH in patients who are unable to tolerate or are unresponsive to other PAH therapies.

How Bosentan 62.5mg Tablets Works

Bosentan 62.5mg Tablets (Bosentan) is an endothelin receptor antagonist. It works by blocking the action of endothelin-1, a potent vasoconstrictor (blood vessel constricting substance). By blocking endothelin-1, bosentan helps to relax and widen blood vessels in the lungs, improving blood flow and reducing blood pressure in the pulmonary arteries.

Storage and Handling of Bosentan 62.5mg Tablets

Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Dispose of unused medication properly.

Dosage of Bosentan 62.5mg Tablets

    Dosage and frequency are determined by the physician based on individual patient needs and response.

    Typically administered orally, usually twice daily.

    Always follow your doctor's instructions carefully.

Side effects of Bosentan 62.5mg Tablets

    Headache

    Flushing

    Lower extremity edema (swelling)

    Nasopharyngitis (common cold)

    Dizziness

    Fatigue

    Nausea

    Elevated liver enzymes (requiring monitoring)

    Anemia

    Elevated creatinine levels (kidney function indicator)

    Rare but serious: Liver failure

Safety Consideration or Warnings
    Alcohol Consumption

    Alcohol consumption may increase the risk of side effects. Consult your doctor.

    Driving or operating Machinery

    Bosentan may cause dizziness or fatigue. Avoid driving or operating machinery until you know how it affects you.

    Pregnant & Breastfeeding Women

    Bosentan is contraindicated in pregnancy due to teratogenic effects (harm to a developing fetus). It is also contraindicated during breastfeeding. Effective contraception is crucial.

    Children

    Safety and efficacy in children have not been established.

    Kidney

    May affect kidney function. Regular monitoring of kidney function is necessary.

    Liver

    Bosentan can cause liver damage. Regular monitoring of liver enzymes is required.

References

    Your doctor or pharmacist

    The prescribing information provided with the medication

    Reputable medical websites (e.g., FDA, reputable medical journals)

Last Updated On 14 Jul. 2025 | 07:32 AM (IST)
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