Bortezomib

Is the active ingredient.

Multiple myeloma (a type of blood cancer)

Mantle cell lymphoma (a type of nonHodgkin lymphoma)

Bortenat 2mg Inj (Bortezomib) is a proteasome inhibitor. Proteasomes are protein complexes within cells that break down unwanted proteins. By inhibiting these proteasomes, bortezomib causes the accumulation of harmful proteins within cancer cells, leading to their death. This is particularly effective against myeloma and lymphoma cells.

Store bortezomib at a controlled room temperature between 20°C and 25°C (68°F and 77°F). Protect from light and moisture. Dispose of unused medication properly according to your pharmacist's or healthcare provider's instructions.

Dosage and administration vary greatly depending on the specific condition being treated, the patient's overall health, and other medications they are taking. It is crucial to follow your doctor's precise instructions.

Bortezomib is typically administered intravenously (IV) by a healthcare professional.

Some formulations may be administered subcutaneously (under the skin).

Peripheral neuropathy (tingling, numbness, or pain in the hands and feet)

Thrombocytopenia (low platelet count)

Fatigue

Nausea and vomiting

Diarrhea

Constipation

Rash

Elevated liver enzymes

Cardiac problems (in rare cases)

Alcohol Consumption

Alcohol consumption may exacerbate some side effects, particularly nausea and fatigue. Consult your doctor.



While Driving or operating Machinery

Bortezomib can cause fatigue and neuropathy, potentially impairing driving or operating machinery. Avoid if experiencing these side effects.



Pregnant & Breastfeeding Women

Bortezomib is not recommended during pregnancy or breastfeeding due to potential harm to the fetus or infant. Discuss alternatives with your doctor.



Children

The safety and efficacy of bortezomib in children have not been fully established.



Kidney

Kidney function should be monitored regularly as bortezomib is excreted through the kidneys. Dosage adjustment may be necessary in patients with impaired kidney function.



Liver

Liver function should be monitored regularly, as bortezomib can affect liver enzymes. Dosage adjustment may be necessary in patients with impaired liver function.

Your doctor and pharmacist

The prescribing information (package insert) provided with your medication

Reputable medical websites such as the National Cancer Institute (NCI) and the Mayo Clinic